The Phytochemistry laboratory develops commercially viable processes for the optimum extraction of medicinal plants where active constituents (markers) are known. The plant extracts generated thereof are standardized to contain known amount(s) of biologically active constituent(s). For plants where active / markers are not known, bioactivity guided fractionations are undertaken and active / bio-markers are isolated for the purpose of standardization. Chromatographic techniques like column, flash, MPLC, Preparative HPLC are employed for isolating constituents. The isolated single chemical entities are thoroughly characterized using the conventional spectroscopic (UV, IR, NMR & Mass spectroscopy) and chromatographic techniques.
Areas of competence
Identification of crude drugs using pharmacognostic techniques:
- Isolation of markers for standardization of herbal products.
- Bioactivity guided fractionations of herbs to isolate their bio-active compounds.
- Development of extraction procedures for medicinal plants.
- Isolation of phytochemicals of high purity for use as chromatographic reference standards.